Funktionelle Insulintherapie / Functional Insulin Treatment

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Functional Insulin Treatment: Competent Patient Leadership

Focus of our research
  1. Translational research in effective cardiovascular prevention based on rehabilitation engineering in structured patient education.
  2. Assessment of incipient cardiovascular damage as caused by diabetes, hyperlipidemia and hypertension, using heart rate variability and/or 24h ambulatory blood pressure monitoring.
  3. Development of media for cardiovascular prevention and patient education
  4. Hypoglycemia unawareness and restoration of hypoglycemia awareness in type 1 diabetes mellitus, hypoglycemia threshold sensor
  5. Algorithms for management of diabetes in pregnancy, normalization of pregnancy outcomes.
  Rehabilitation engineering:

  1. Development of appropriate, end-user suitable devices and procedures for effective treatment of diabetes, hypertension, obesity and hyperlipidemia
  2. “Closing the loop” -- algorithms for insulin dosage
First publication of Kinga Howorka on FIT (ONIS) in 1984

PUBLIKATIONEN / PUBLICATIONS


 

Modified orthostatic load for spectral analysis of short-term heart rate variability improves the sensitivity of autonomic dysfunction assessment.

Howorka K, Pumprla J, Jirkovska A, Lacigova S, Nolan J.

J Diabetes Complications. 2008 Dec 4. [Epub ahead of print]

PMID: 19062311 [PubMed - as supplied by publisher]



 

Computerized generation of circadian sensor modal days with continuous glucose monitoring for comparison of various insulin regimens based on insulin glargine in type 1 diabetes.

Howorka K, Pumprla J, Gabriel M, Thoma H, Schabmann A.

Int J Artif Organs. 2003 Aug;26(8):728-34.

PMID: 14521170 [PubMed - indexed for MEDLINE]




 

Functional assessment of heart rate variability: physiological basis and practical applications.

Pumprla J, Howorka K, Groves D, Chester M, Nolan J.

Int J Cardiol. 2002 Jul;84(1):1-14. Review.

PMID: 12104056 [PubMed - indexed for MEDLINE]


 

Normalization of pregnancy outcome in pregestational diabetes through functional insulin treatment and modular out-patient education adapted for pregnancy.

Howorka K, Pumprla J, Gabriel M, Feiks A, Schlusche C, Nowotny C, Schober E, Waldhoer T, Langer M.

Diabet Med. 2001 Dec;18(12):965-72.

PMID: 11903395 [PubMed - indexed for MEDLINE]

Related Articles



 

Dealing with ceiling baseline treatment satisfaction level in patients with diabetes under flexible, functional insulin treatment: assessment of improvements in treatment satisfaction with a new insulin analogue.

Howorka K, Pumprla J, Schlusche C, Wagner-Nosiska D, Schabmann A, Bradley C.

Qual Life Res. 2000;9(8):915-30.

PMID: 11284211 [PubMed - indexed for MEDLINE]

 



 

Empowering diabetes out-patients with structured education: short-term and long-term effects of functional insulin treatment on perceived control over diabetes.

Howorka K, Pumprla J, Wagner-Nosiska D, Grillmayr H, Schlusche C, Schabmann A.

J Psychosom Res. 2000 Jan;48(1):37-44.

PMID: 10750628 [PubMed - indexed for MEDLINE]

 



 

Decrease of vigilance assessed by EEG-mapping in type I diabetic patients with history of recurrent severe hypoglycaemia.

Howorka K, Pumprla J, Saletu B, Anderer P, Krieger M, Schabmann A.

Psychoneuroendocrinology. 2000 Jan;25(1):85-105.

PMID: 10633537 [PubMed - indexed for MEDLINE]

 



 

[University research and education in rehabilitation technology: inducing ISO 9001 conformity and initial experiences with a certified quality management system]

Howorka K, Pumprla J, Kletschka G, Thoma H.

Biomed Tech (Berl). 1998;43 Suppl:570-1. German. No abstract available.

PMID: 9859496 [PubMed - indexed for MEDLINE]



 

[Development of an analytic standard for evaluating heart rate variability in cardiovascular autonomic neuropathy in diabetes: comparison of short-term spectral analysis with Ewing's standard battery of reflex tests as reference method]

Howorka K, Pumprla J, Schabmann A, Thoma H.

Biomed Tech (Berl). 1998;43 Suppl:568-9. German. No abstract available.

PMID: 9859495 [PubMed - indexed for MEDLINE]



 

Optimal parameters of short-term heart rate spectrogram for routine evaluation of diabetic cardiovascular autonomic neuropathy.

Howorka K, Pumprla J, Schabmann A.

J Auton Nerv Syst. 1998 Apr 30;69(2-3):164-72.

PMID: 9696273 [PubMed - indexed for MEDLINE]

 



 

Weak relationship between symptom perception and objective hypoglycaemia-induced changes of autonomic function in hypoglycaemia unawareness in diabetes.

Howorka K, Heger G, Schabmann A, Skrabal F, Pumprla J.

Acta Diabetol. 1998 Apr;35(1):1-8.

PMID: 9625282 [PubMed - indexed for MEDLINE]

 



 

[ISO 9001 conformity in research, teaching and rehabilitation]

Howorka K, Kletschka G, Pumprla J, Thoma H.

Biomed Tech (Berl). 1998 Jan-Feb;43(1-2):19-24. German.

PMID: 9542284 [PubMed - indexed for MEDLINE]

 



 

Effects of physical training on heart rate variability in diabetic patients with various degrees of cardiovascular autonomic neuropathy.

Howorka K, Pumprla J, Haber P, Koller-Strametz J, Mondrzyk J, Schabmann A.

Cardiovasc Res. 1997 Apr;34(1):206-14.

PMID: 9217892 [PubMed - indexed for MEDLINE]

Free article at journal site



 

Severe hypoglycaemia unawareness is associated with an early decrease in vigilance during hypoglycaemia.

Howorka K, Heger G, Schabmann A, Anderer P, Tribl G, Zeitlhofer J.

Psychoneuroendocrinology. 1996 Apr;21(3):295-312.

PMID: 8817728 [PubMed - indexed for MEDLINE]

 



 

EEG topography during insulin-induced hypoglycemia in patients with insulin-dependent diabetes mellitus.

Tribl G, Howorka K, Heger G, Anderer P, Thoma H, Zeitlhofer J.

Eur Neurol. 1996;36(5):303-9.

PMID: 8864713 [PubMed - indexed for MEDLINE]

 



 

Monitoring set-up for selection of parameters for detection of hypoglycaemia in diabetic patients.

Heger G, Howorka K, Thoma H, Tribl G, Zeitlhofer J.

Med Biol Eng Comput. 1996 Jan;34(1):69-75.

PMID: 8857314 [PubMed - indexed for MEDLINE]

 



 

[Modular education in diabetes and pregnancy: analysis of results of 58 pregnancies in diabetic patients with functional insulin treatment]

Howorka K, Pumprla J, Feiks A, Schlusche C, Nowotny C, Ulm M, Schober E, Bernaschek G.

Geburtshilfe Frauenheilkd. 1996 Jan;56(1):41-9. German.

PMID: 8852785 [PubMed - indexed for MEDLINE]



 

Feasibility and efficacy of intensive insulin therapy in type 1 diabetes mellitus in primary care.

Fasching P, Derfler K, Maca T, Kurzemann S, Howorka K, Schneider B, Zirm M, Waldhäusl W.

Diabet Med. 1994 Nov;11(9):836-42.

PMID: 7705019 [PubMed - indexed for MEDLINE]



 

Phases of functional, near-normoglycaemic insulin substitution: what are computers good for in the rehabilitation process in type I (insulin-dependent) diabetes mellitus?

Howorka K, Thoma H, Grillmayr H, Kitzler E.

Comput Methods Programs Biomed. 1990 Jul-Aug;32(3-4):319-23.

PMID: 2249431 [PubMed - indexed for MEDLINE]

 



 

[Functional rehabilitation using technical aids--a new strategy for medical technicians]

Thoma H, Howorka K, Holle J, Girsch W, Lanmüller H, Mayr W.

Biomed Tech (Berl). 1990;35 Suppl 2:254-5. German. No abstract available.

PMID: 2224018 [PubMed - indexed for MEDLINE]


 

[Insulin-dependent diabetes mellitus: minimizing the perinatal risk by subsequent euglycemia]

Feiks AJ, Howorka K, Nowotny C, Waldhäusl W.

Gynakol Rundsch. 1989;29(2):120-7. German. No abstract available.

PMID: 2661347 [PubMed - indexed for MEDLINE]



[Conventional or functional insulin therapy?]

Waldhäusl W, Howorka K, Bratusch-Marrain P.

Wien Klin Wochenschr. 1988 Jun 24;100(13):430-5. Review. German.

PMID: 3043912 [PubMed - indexed for MEDLINE]



 

[Type I diabetes mellitus and pregnancy: an interdisciplinary management program]

Feiks A, Howorka K, Nowotny C, Dadak C, Waldhäusl W.

Wien Klin Wochenschr. 1987 Apr 3;99(7):228-32. German.

PMID: 3296470 [PubMed - indexed for MEDLINE]



Near-normoglycaemia and microvascular complications.

Mühlhauser I, Bruckner J, Howorka K.

Diabetologia. 1987 Jan;30(1):47-8. No abstract available.

PMID: 3552820 [PubMed - indexed for MEDLINE]



Diabetes care in rural area: clinical and metabolic evaluation.

Derfler K, Waldhäusl W, Zyman HJ, Howorka K, Holler C, Freyler H.

Diabetes Care. 1986 Sep-Oct;9(5):509-17.

PMID: 3533476 [PubMed - indexed for MEDLINE]

 



 

Failure and efficacy of insulin therapy in insulin dependent (type I) diabetic patients.

Waldhäusl W, Howorka K, Derfler K, Bratusch-Marrain PR, Holler C, Zyman H, Freyler H.

Acta Diabetol Lat. 1985 Oct-Dec;22(4):279-94.

PMID: 3914155 [PubMed - indexed for MEDLINE]

 


 

Multicomponent system for normoglycemic insulin substitution in type 1 diabetic outpatients.

Howorka K, Stöhr H, Thoma H, Waldhäusl W.

Life Support Syst. 1985;3 Suppl 1:540-5. No abstract available.

PMID: 3916618 [PubMed - indexed for MEDLINE]

 

(c) 2005-2022 by Kinga Howorka, Jiri Pumprla
Research Group Functional Rehabilitation and Group Education eV., and
Medical University Vienna, Austria